Aseptic transfer of items
2026-1-9
Teling Hydrogen Peroxide Sterilization Technology
Efficient, safe solutions for multi-space item aseptic transfer
Technology Overview
Teling Hydrogen Peroxide Sterilization Technology is an advanced disinfection solution specifically designed for safe item transfer between areas with different cleanliness levels. This technology uses vaporized hydrogen peroxide (VHP) or dry fog hydrogen peroxide methods to achieve efficient surface sterilization, ensuring materials can enter high-level critical areas from unclassified or low-cleanliness zones without introducing contamination.
VHP transfer windows using vaporized hydrogen peroxide have been maturely applied in developed countries, achieving a 6-log reduction against Geobacillus stearothermophilus (MESALABS/ATCC7953), ensuring the safety of aseptic transfer.
Teling Biological Hydrogen Peroxide Sterilizer provides complete solutions for terminal disinfection. Its technology is based on the strong oxidizing properties of hydrogen peroxide, effectively killing various microorganisms including bacteria, viruses, fungi, and spores. Hydrogen peroxide is chemically active, easily decomposing into oxygen and water, causing no secondary pollution to the environment, making it a clean, green chemical disinfectant.
Core Technical Advantages
Efficient Sterilization
Vaporized hydrogen peroxide achieves 6-log reduction against Geobacillus stearothermophilus, effectively killing various microorganisms including bacteria, viruses, fungi, and spores.
Safe & Eco-friendly
Hydrogen peroxide easily decomposes into oxygen and water, leaving no harmful residues, with safe concentrations meeting occupational exposure standards (1ppm for 8-hour exposure).
Good Material Compatibility
Suitable for most metals and plastic materials, safe for various surfaces including stainless steel, plastic, and glass.
Fast Cycle
Dry fog sterilization system completes the entire transfer chamber sterilization in just 20-30 minutes, significantly improving production efficiency.
Intelligent Operation
Equipment features intelligent control system, supporting wireless remote control, multi-room disinfection parameter settings, with simple operation.
Easy Validation
Sterilization effect is easy to validate, compliant with GMP requirements, meeting high standards in pharmaceutical and medical industries.
Working Principle
Teling Hydrogen Peroxide Sterilization Technology is based on the strong oxidizing properties of hydrogen peroxide. Through vaporization or dry fogging methods, hydrogen peroxide solution is converted into extremely fine particles that can be evenly distributed throughout the sterilization space, including complex surfaces and hard-to-reach areas.
Vaporized hydrogen peroxide in gaseous state at room temperature has greater sporicidal capability than in liquid state. It generates free hydroxyl radicals that attack cellular components including lipids, proteins, and DNA structures, achieving complete sterilization requirements.
Teling Biological TL-QB1500 equipment uses Venturi atomization principle, requiring no heating for vaporization, spraying low-concentration hydrogen peroxide disinfectant solution into small droplets averaging 1-5 microns, which evenly diffuse into the sterilization space and onto object surfaces for disinfection and sterilization.
Atomization Process
Hydrogen peroxide solution is atomized into 1-5 micron fine particles
Even Distribution
Dry fog particles undergo Brownian motion in space, evenly covering all surfaces
Microbial Elimination
Hydrogen peroxide decomposes to produce hydroxyl radicals that destroy microbial cell structures
Safe Decomposition
Hydrogen peroxide naturally decomposes into water and oxygen, leaving no harmful residues
Application Scenarios
Teling Hydrogen Peroxide Sterilization Technology is widely used for aseptic item transfer in the following scenarios:
VHP Pass-through Window Applications
VHP pass-through windows are specifically designed for item transfer between areas of different cleanliness levels, enabling complete surface sterilization of items to prevent cross-contamination. The pass-through windows feature an interlock system that prevents opening during sterilization, ensuring operational safety.
The system uses external or built-in hydrogen peroxide generators, operating at low temperature and atmospheric pressure, making it environmentally friendly, efficient, and highly suitable for use in sterile pharmaceutical environments.
Space Sterilization Applications
Teling Hydrogen Peroxide Sterilization Technology can be used for terminal disinfection of entire rooms or enclosed spaces, such as sterile production workshops, hospital ICUs, and operating rooms. The system ensures complete sterilization of all surfaces within the space, including walls, ceilings, and equipment surfaces.
The dry fog hydrogen peroxide sterilization system combined with space sporicides can meet the disinfection and sterilization requirements of clean areas, easily passing GMP validation, and is highly favored by pharmaceutical companies and enterprises requiring GMP certification.
Equipment Internal Sterilization
Teling Hydrogen Peroxide Sterilization Technology can be safely used for internal sterilization of biosafety cabinets, isolators, freeze dryers, and other equipment. Through pipeline circulation methods, it achieves complete disinfection of complex internal structures of equipment.
The TL-V500 model equipment features both space and pipeline circulation modes, capable of efficient sterilization of 500 cubic meter spaces or equipment interiors.
Comparison with Traditional Methods
| Comparison Item | Teling Hydrogen Peroxide Sterilization Technology | Traditional Sterilization Methods (UV/Ozone) |
|---|---|---|
| Sterilization Effect | 6-log reduction, including spores | Limited, poor effect on spores |
| Sterilization Time | 20-30 minutes | Several hours to days |
| Material Compatibility | Good, non-corrosive | May cause material aging |
| Safety | No harmful residues, decomposes to water and oxygen | Ozone is toxic, requires thorough ventilation |
| Operation Convenience | Fully automated operation, intelligent control | Complex operation, requires professional personnel |
| Validation Difficulty | Easy to validate, compliant with GMP requirements | Complex validation, effects difficult to ensure |
With the implementation of new GMP regulations, ozone and UV methods no longer meet the requirements for sterility, necessitating upgrades and modifications. The dry fog hydrogen peroxide sterilization system is an excellent alternative to traditional sterilization methods and the best replacement for VHP transfer chamber sterilization.
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